1 – Research Associate in Plant Systems Biology
Applications are invited for a Post-doctoral Research Associate position in the group of Dr James Locke at the Sainsbury Laboratory, to carry out fundamental research in the field of plant systems biology. The project will focus on understanding plant gene regulation at the single-cell level. The project will use single-cell time-lapse microscopy and single-cell RNA-seq to examine the mechanisms underlying dynamic and noisy gene regulation in plants. The project requires both experimental and quantitative skills.
The Locke group encourages a collaborative and open research approach and has a strong record of training interdisciplinary postdocs to gain group leader positions. The direction of the project will be developed with the successful candidate.
Applicants must have a PhD in Plant Development, Systems Biology, Biology, Physics, or related field and have expertise in experimental systems biology.
Where a PhD has yet to be awarded the appointment will initially be made at Research Assistant level (Grade 5) and amended to Research Associate (Grade 7) upon the award of PhD.
Successful candidates will have experience in systems biology approaches such as time-lapse microscopy and assays for gene expression, as well as experience of quantitative analysis of data, e.g. automated image processing and/or quantitative image analysis. Experience in Matlab, R or an equivalent software package is desirable. Knowledge of theoretical approaches such as computational modelling is also desirable. Publications in the field of systems or developmental biology are required.
Good communication skills are essential as the post holder will need to work well in a team and collaborate with other researchers in the Institute. Candidates should also demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).
Informal scientific enquiries should be directed to Dr Locke at: James.Locke@slcu.cam.ac.uk
The post is available immediately. Available for 2.5 years in the first instance.
We particularly welcome applications from women and candidates from a BME background for this vacancy.
Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.
Please quote reference PT31062 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further information
Apply online. Closing date 25 May 2022
2 – Research Associate in Computational Biology (Plant Circadian Clock)
Applications are invited for a BBSRC funded Post-doctoral Research Associate position to work in the group of Dr James Locke at the Sainsbury Laboratory, in close collaboration with Professor Alex Webb of the Department of Plant Sciences, focused on the modelling of the circadian (24-hour) clock in plants.
The position involves developing the first model of the Wheat circadian clock. Wheat is a key crop and understanding the clock in wheat will have broad significance as the clock controls many key processes in plants. The candidate will analyse new RNA-seq clock data collected in Professor Webb’s group and use machine learning techniques to develop an optimised computational model of the core wheat clock network. In addition, the successful candidate will investigate the effects of temperature and noise in gene regulation on the wheat clock.
The successful candidate will have experience of modelling gene regulatory networks and should have experience of ODE modelling. Candidates must have extensive modelling experience in computer languages such as Matlab, C++, Python or R., and have at least one publication in the field of computational biology or systems biology.
Applicants must have, or be close to obtaining, a PhD in a related field such as systems biology, mathematics, or physics. Good communication skills are essential as the post holder will need to work well in a team and collaborate with wet-lab researchers. Candidates should also demonstrate a history of science communication (e.g. presentations, outreach activities, teaching).
Where a PhD has yet to be awarded the appointment will initially be made at Research Assistant level (Grade 5) and amended to Research Associate (Grade 7) upon the award of PhD.
The Laboratory provides a welcoming and collaborative environment with a wide-range of family-friendly benefits and development opportunities.
Informal scientific enquiries should be directed to Dr Locke at: James.Locke@slcu.cam.ac.uk
The post is available immediately.
Fixed-term: The funds for this post are available for 2.5 years in the first instance.
We particularly welcome applications from women and candidates from a BME background for this vacancy.
Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.
Please quote reference PT30967 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.