In this PhD project (P06), we study the interaction of several compartments (e.g. skin and colon) and effects of the microbiome for alpha-Gal allergy development (red meat allergy). We already established protocols for sensitization and anaphylactic responses of alpha-Gal deficient pigs.
Our next aim is to establish germ-free (gnotobiotic) pig models to evaluate the influence of microbial consortia on sensitization and allergy development. We plan to perform fecal microbial transfers and further apply cutting-edge microbiota and metabolite profiling methodologies to identify protective microorganisms and molecules. The perspective of this project is to fundamentally understand underlying immune cell mechanisms and to implement a microbiome-based approach to inhibit allergy development.
Applicants should hold at least a Master degree in Veterinary science, Microbiology, (Molecular) Biology or Biotechnology and have a strong interest in Animal models, Microbiology and Immunology. They should be fluent in spoken and written English. Experience in the fields of veterinary sciences or large animal models is of great advantage.
Salary and duration
Payment is according to the wage agreement of the civil service TV-L, 65% of E13 for PhD student positions for 4 years. Please note that there are no additional postgraduate degree fees required for international candidates.
Applicants are asked to send one pdf file to the contact person. The file includes
• Cover letter
• Curriculum Vitae
• Copies of academic degrees and transcripts of records
• Contact information for at least one letter of recommendation
• List of publications with link for downloading (Do not include your publications in the pdf file) Send application to:
Konrad.firstname.lastname@example.org Application deadline March 1st 2023
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