The German Cancer Research Center is the largest biomedical research institution in Germany. With approximately 3,000 employees, we operate an extensive scientific program in the field of cancer research. Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).
For the research group of Prof. Dr. Philipp Greif (Department of Medicine III, LMU Klinikum) at the DKTK partner site Munich the German Cancer Research Center is seeking a PhD Student in Bioinformatics. (Ref-No. 2023-0054)
The research group has long standing expertise in the molecular dissection of tumor diseases und functional modeling of somatic alterations in cancer. The research is focused on the pathogenesis of acute leukemia and tumor metabolism. In collaboration with the Comprehensive Cancer Center Munich (CCC Munich), we analyze the molecular profiles of advanced tumors across entities, providing the basis for personalized treatment strategies.
Recent selected publications from our research group: 1. Kerbs et al. Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements. Haematologica. 2022 Jan 1;107(1):100-111. 2. Opatz et al. The clinical mutatome of core binding factor leukemia. Leukemia. 2020 Jun;34(6):1553-1562. 3. Greif et al. Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients. Clin Cancer Res. 2018 Apr 1;24(7):1716-1726.
Job description:
- Analysis of NGS data from tumor patients at the DKTK partner site Munich (LMU)
- Modeling and integration of multiple data levels (e.g. exome, transcriptome, DNA-methylation, single-cell genomics)
- Maintenance and further development of a genomics platform
Requirements:
- M.Sc. in bioinformatics or equivalent
- Excellent programming and analytical skills
- Excellent command of English
- Strong ability to work in a multidisciplinary team of biologists, physicians and bioinformaticians
- Background knowledge in cancer genetics is an advantage
We offer:
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Access to international research networks
- Doctoral student payment including social benefits
- Flexible working hours
- Comprehensive training and mentoring program through the Helmholtz International Graduate School
The position is limited to 3 years.
Important notice:
The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ. For further information please contact: Christine Koppenhöhl, phone +49 (0)89/4400-54627.
The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.
To apply for a position please use our online application portal APPLY NOW. We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebsforschungszentrum, Personalabteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.