Postdoctoral Positions: The Institute for Molecular Plant Physiology invites applications for three postdoctoral positions in Plant Proteostasis, available in the group of Prof. Marco Trujillo at the RWTH University Aachen.
ABOUT US: Research in the Trujillo lab focuses on understanding ubiquitin signalling and its roles in the regulation of immune responses and general protein homeostasis (Brillada et al. Essays in Biochem. 2022; Trenner et al. Annual Reviews 2021; Trujillo et al. New Phytologist 2021).
Previous and ongoing research in the Lab has uncovered key roles of ubiquitination in the regulation of intracellular vesicle transport (Saeed et al. Current Biology 2023), autophagy (Brillada et al. Plant Cell 2023), as well as its interplay with signalling triggered by immune receptor kinases (Yu et al. EMBO 2022).
POSITION SUMMARY: The successful candidates will work on exciting projects that investigate different aspects of plant proteostasis:
Project 1. Investigate mechanisms of ubiquitination-mediated regulation of endocytosis during the immune response (three years)
Project 2: Elucidate ubiquitin signalling code and crosstalk with immune receptor-triggered signalling from a systems-based perspective (two years)
Project 3: Development of a targeted protein degradation (TPD) chassis and development of PROTACs in cooperation with an industry partner (two years).
The position will be a fantastic opportunity for candidates to broaden their skillset by working in a multidisciplinary lab using state-of-the-art technologies combining protein Biochemistry and cell biology. Coupled with this exciting area of biological focus, the project will provide excellent opportunity for career development with mentoring support to reach career aspirations and with generous consumable support.
REQUIREMENTS
We are looking for an early career researcher with a passion for ubiquitin biology. Expertise in protein biochemistry or cell biology are a plus but not a requirement. Additional requirements are a PhD (full award) and excellent English.
ADDITIONAL INFORMATION: Salary will be according to the German Public Sector Agreement (E13, 100%) commensurate to qualifications and experience.
To apply: Please include for your application in a single file: Cover letter detailing your motivation for applying, CV, copy of PhD degree, name and address of three referees in a single file. Send applications to Ms. Katrin Wysgol (Katrin.Wysgol@rwth-aachen.de ) until August 13. For further information contact Marco Trujillo directly mtrujillo@bio3.rwth-aachen.de.